The Detroit Lions and the Buffalo Bills meet Thursday for their Week 2 game in Orchard Park, New York. Kickoff is scheduled for 8:15 p.m. ET.

Heading into Week 2 of the 2026 NFL season, the Detroit Lions face another tough challenge, as the Buffalo Bills await Dan Campbell's squad. Detroit are currently 4.5-point underdogs against their AFC East opponent,

The Detroit Lions will be without two starting offensive linemen against the Buffalo Bills on Thursday night. Detroit ruled out rookie offensive tackle Blake Miller (knee) and guard Christian Mahogany (hip) with injuries.

Larry Hartstein reveals his picks for Detroit Lions vs. Buffalo Bills in the 2026 Week 2 'Thursday Night Football' matchup

The Jets return home for the first time in 2026 with a 1-0 record, but the Packers present a different challenge after a stunning Week 1 collapse.

The Green Bay Packers' second game of the season, and second on the road, is one of only six noon games they'll play this year. The Packers will meet the New York Jets at noon Sep

The Green Bay Packers will play at the New York Jets on Sunday. Here's the date, time and TV information plus connections and more.

The Green Bay Packers seemed like they were just capable enough to solve Brian Flores’ pressure packages at the start of yesterday’s season opener.Then the protection unraveled, and an ugly number from their 39-22 loss to the Minnesota Vikings puts the downfall in perspective.

The Tennessee Titans host the Philadelphia Eagles this week in a matchup that pits the Titans' weaknesses against well-known Eagles strengths.

The Tennessee Titans got smoked by the New york Jets in Week 1, but a win in Week 2 against the Philadelphia Eagles would totally right the ship immediately. The vib

The Eagles won in Week 1, but they showed a clear liability on offense. The Titans have to take advantage of it if they're going to take a step forward in Week 2.

Tennessee Titans vs Philadelphia Eagles odds for NFL Week 2 game betting, including point spread, moneyline, over/under for Sunday, Sept. 20, 2026.

The Seattle Seahawks have ruled starting quarterback Sam Darnold out in their Week 2 matchup against the Arizona Cardinals with a glute injury.

It’s a very different report than the one we got from Pro Football Talk’s Mike Florio, who said Darnold — injured on the first drive of the regular season — could be sidel

Coach Mike Macdonald's latest on Sam Darnold injury, Seattle Seahawks plan at quarterback, Wednesday, Sept. 16, 2026, at the Virginia Mason Athletic Center in Renton.

Mike Macdonald is in a situation that no head coach wants to be in. His starting quarterback is currently out of commission with an injury. Sam Darnold went down early in Week 1 with a glute injury, but there have been mostly positive developments since then.

US Open runner-up Ben Shelton withdrew from the Laver Cup and will be replaced by 16th-ranked Brandon Nakashima on Team World, organizers announced Thursday.

Ben Shelton, subcampeón del Abierto de Estados Unidos, se retiró de la Copa Laver y será reemplazado por Brandon Nakashima, 16to del ranking, en el Equipo Mundo, anunciaron los organizadores el jueves.

U.S. Open runner-up Ben Shelton withdrew from the Laver Cup and will be replaced by 16th-ranked Brandon Nakashima on Team World

Ben Shelton has withdrawn from next week's Laver Cup, just days after reaching the US Open final. The young American went up against Alexander Zverev in his maiden Grand Slam final, but was unable to get past his German opponent.

New York Giants QB Jaxson Dart breaks down a three-play sequence to Devin Singletary in Week 1 that many believed were the same play.

New York Giants quarterback Jaxson Dart had a brilliant showing in the team's Week 1 over the Dallas Cowboys, going 23-for-29 with 230 yards and three touchdowns while also adding 54 rushing yards. It was arguably the best performance of Dart's career,

The New York Giants got a convincing win against the Dallas Cowboys in Week 1, and many people are excited to see if they can keep this momentum going into the remainder of the season. They’ll have another big test in Week 2 against the Los Angeles Rams,

Giants coach John Harbaugh didn’t need to watch the tape of Sunday night’s massive win over the Cowboys to know how Jaxson Dart played. Dart — the Giants’ prized second-year quarterback — tore up Dallas’ still-rebuilding defense and put together the best game of his young career.